A metal cylinder is held in each hand for 20 minutes, while the device repeatedly sweeps through the wide range of pathogenic frequencies. These frequencies are not felt by most people, nor are they audible. Sessions are repeated one or two times a week until clinical improvement occurs, then possibly continued once a week for a few weeks to ensure continued success. Rife treatment can be easily combined with other therapies or treatments. One may experience symptoms of detoxification initially which may include headaches, lassitude or body aches, but these are only temporary and are usually followed by a sense of well-being. It is vitally important to ensure adequate intake of pure water [2 liters/24 hours] after each treatment to flush out dead organisms and products of toxic waste.